PT-141 Peptide | 10mg | Research Grade

PT-141 UK availability is one of the most common research queries we receive — this page covers everything you need before ordering, including mechanism, purity testing, and storage guidance.

What Is PT-141?

PT-141, more widely known by its chemical name Bremelanotide, is a synthetic cyclic peptide derived from Melanotan II, itself modelled on the naturally occurring hormone alpha-melanocyte-stimulating hormone (alpha-MSH). Bremelanotide is also the peptide underlying the licensed pharmaceutical Vyleesi, though ApexPure supplies PT-141 exclusively as an unformulated research chemical, entirely separate from that clinical product.

ApexPure supplies PT-141 10mg as a lyophilised, research-grade compound strictly for laboratory research applications. Unlike Melanotan II, which engages melanocortin receptors broadly across both central and peripheral pathways, PT-141 is studied for its more selective agonism at the MC3R and MC4R receptor subtypes, both expressed predominantly in the central nervous system.

Also Known As

PT-141 appears in research and clinical literature under several names, which is useful to know when searching for related studies: Bremelanotide (its chemical/generic name), Vyleesi (the licensed pharmaceutical formulation, not sold by ApexPure), and occasionally as a Melanotan II metabolite, referencing its structural origin.

PT-141 vs Melanotan II — Research Comparison

Research Applications

Research literature has examined PT-141 in relation to central nervous system melanocortin signalling, with particular research interest in MC3R and MC4R activation pathways studied in neuroendocrine and behavioural research models. Comparative studies have investigated its receptor-binding profile against Melanotan II, exploring how this more selective agonism differs from the broader melanocortin receptor activity associated with its parent compound, and its relevance to arousal-pathway and dopamine-release research.

Background & Research History

PT-141 was developed as researchers sought to isolate a specific fragment of Melanotan II responsible for central melanocortin receptor activity, separate from the peripheral pigmentation effects that characterised the parent compound. This research effort produced a peptide with a narrower, more targeted receptor profile, and it has since become a frequently referenced compound in neuroendocrine and central melanocortin pathway literature, eventually informing the development of the licensed pharmaceutical Vyleesi.

Purity & Third-Party Testing

Every ApexPure batch of PT-141 is independently HPLC-verified to a minimum of 99% purity, with a batch-specific Certificate of Analysis available for download directly from this product listing, giving full traceability between testing data and the vial you receive.

Reconstitution & Storage Guidelines

Store the lyophilised vial frozen at -18°C or below, protected from light and moisture. Once reconstituted with bacteriostatic water, refrigerate the solution at 2-8°C and avoid repeated freeze-thaw cycles, which can compromise peptide stability across a research protocol.

Handling Notes for Researchers

PT-141 should be handled only by qualified laboratory personnel using appropriate PPE, in a controlled research environment, following your institution’s documented protocols for reconstitution, handling, and disposal. ApexPure does not provide dosing or administration guidance, as this compound is supplied strictly for laboratory research.

Why Buy PT-141 UK From ApexPure

ApexPure was built around one standard: every batch we sell is independently tested before it reaches your laboratory, and every Certificate of Analysis is published, not hidden behind a support request. PT-141 is frequently compared directly against Melanotan II in receptor-selectivity research, and we test it to the same independent standard as every other compound in our Performance range so comparative data stays reliable. Orders are dispatched from the UK, so researchers avoid the customs delays and cold-chain uncertainty that come with importing from overseas suppliers. If a batch does not meet our purity threshold, it does not go on sale — that is the certification promise behind the ApexPure name. Read more about our testing process, or check our FAQ for common questions about ordering and dispatch. Our facility operates under documented quality-control procedures, with every incoming batch checked against its accompanying Certificate of Analysis before it is released into inventory. We work with independent, third-party laboratories rather than relying on internal or manufacturer-supplied test data, which is a distinction researchers increasingly look for when comparing UK suppliers. Packaging is designed to protect peptide integrity in transit, and orders are typically dispatched within one to two working days of purchase.

Frequently Asked Questions

How does PT-141 differ from Melanotan II?

PT-141 is a fragment derived from Melanotan II, isolated for more selective activity at the MC3R/MC4R receptors in the central nervous system, whereas Melanotan II engages melanocortin receptors more broadly, including peripheral pigmentation pathways.

Is PT-141 the same as Vyleesi?

Bremelanotide is the active peptide behind the licensed pharmaceutical Vyleesi. ApexPure’s PT-141 is an unformulated research chemical sold strictly for laboratory investigation and is entirely separate from that clinical product.

Is PT-141 legal to purchase in the UK?

Yes, as an unlicensed research chemical sold strictly for laboratory and in-vitro research purposes, in line with current UK regulation. It is not licensed for human consumption or clinical use.

What purity standard does ApexPure test PT-141 to?

Every batch is independently HPLC-verified to a minimum of 99% purity before release, with a matched Certificate of Analysis available for download.

This product is sold strictly for laboratory and in-vitro research use only. It is not a drug, food, supplement, or cosmetic, and is not intended for human or veterinary consumption, diagnostic, or therapeutic use. Not for use in humans or animals. Purchaser must be 18+ and confirms this material will be handled only by qualified researchers in a controlled laboratory setting, in accordance with UK law.